INTRODUCTION: This study aims to determine the frequency of thyroid gland invasion in patients with locally advanced laryngeal carcinoma who were treated with total laryngectomy and neck dissection as well as hemi- or total thyroidectomy.
METHODS: Between April 2000 and February 2016, 127 patients (123 males, 4 females; mean age 57 years; range, 41 to 74 years) who underwent total laryngectomy and neck dissection with laryngeal squamous cell carcinoma were retrospectively reviewed in our clinic. Patients demographic characteristics, preoperative tumor stage, postoperative laryngectomy pathology report, tumor invasion, neck lymph node invasion and thyroid gland invasion were evaluated.
RESULTS: In 127 patients, 43 with subglottic extension, extralaryngeal extension and cricothyroid membrane invasion underwent total or hemithyroidectomy in addition to laryngectomy and neck dissection. Squamous cell carcinoma infiltration was found in one patient (2.3%) in the thyroid gland. This patient was diagnosed as T4N1M0 in the pathological stage. Thyroid cartilage invasion and subglottic extension were detected in the preoperative evaluation.
DISCUSSION AND CONCLUSION: Thyroidectomy is performed in our clinic only when subglottic extension, extralaryngeal invasion or cricothyroid membrane invasion is present. Hence, thyroid gland invasion is not common in carcinoma of the larynx. For this reason, we recommend selective thyroidectomy to protect patients from the morbidity of routine thyroidectomy.