Objectives: This study proposed relationship between rhinitis and
hypothyroidism and the possibility of whether hypothyroid patients
with symptoms of rhinitis could recover by treatment are investigated.
Patients and Methods: Twenty-five patients (19 females, 6 males;
mean age 42.2 years; range 19 to 65 years) diagnosed with hypothyroidism
and examined in our clinic by the same doctor between
February 2004 and February 2005 were included in the study. In
order to evaluate the symptoms of the patients, a detailed form
was filled. The degree of symptoms was determined with the visual
analog scale (VAS) by the patients. All patients underwent otorhinolaryngologic
examination including nasal endoscopy where the color
of nasal mucus, turbinate hypertrophy and rhinorrhea were recorded.
Nasal air flows were measured by peak-flow meter. Mucociliary
clearance was measured by the saccharin test. Following all the
measurements, patients were started on oral therapy with levothyroxin
sodium tablets by the ambulatory endocrinology clinic. When
the degree of serum thyroid stimulating hormone level fell below
4 μIU/dl, each complaint was re-evaluated by VAS and the examinations
were repeated. The measurements of nasal peak flow meter
and saccharine clearance time are repeated.
Results: The most frequent complaints of the patients were nasal
obstruction (48%), headaches (20%) and rhinorrhea (16%). Following
treatment, the complaints resolved significantly (p=0.005). The difference
between the turbinate hypertrophy and mucosal pallor before
and after treatment was significant (p=0.005). The clearance time
difference before and after treatment was highly significant (p=0.001).
The nasal peak flow meter results after treatment were also significantly
Conclusion: Besides other examinations, thyroid functions should
also be assessed in patients presenting with rhinitis symptoms.
FREE FULL TEXTAnahtar Kelimeler: Hipotiroidizm; burun tıkanıklığı; rinit.