Nasal natural killer T-cell lymphoma is a very aggressive
and destructive disease with a poor prognosis. We
hereby present two male patients in whom diagnostic
problems and a mortal course were encountered. One
patient (age 31 years) had progressive ulceration in the
nasal area. Two biopsies that had been taken elsewhere
were inconclusive. The other patient (age 40
years) was referred with a previous histopathologic
diagnosis of squamous cell carcinoma. He complained
of an unhealing wound in the hard palate. Biopsies
were repeated in each case. Diagnosis was made by
immunohistochemical examination. Both patients died
shortly after the diagnosis. The importance of obtaining
an adequate and deep biopsy sample and employing
sophisticated immunohistochemical examination is
emphasized for accurate diagnosis.
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Anahtar Kelimeler: Granülom, ölümcül orta hat/patoloji/tanı;öldürücü hücre, doğal; lenfoma, T-hücreli/patoloji/mortalite;burun neoplazmları/patoloji.