ORIGINAL ARTICLE | |
1. | Prevalence of chronic otitis media in the young male population in Turkey Murat Salihoğlu, Ümit Hardal, Hakan Cıncık Pages 273 - 276 FREE FULL TEXT Objectives: In this study, we investigate the prevalence of chronic otitis media (COM) in young men. Patients and Methods: Twenty thousand consecutive young men (mean age 22 years) who were under election for high performance military positions were examined by two otolaryngologists in the Military Hospital, İzmir. The otologic examination findings were noted. We evaluated the patients who have tympanic membrane perforation, retraction, adhesion, myringosclerosis and the patients who had underwent surgery before. Results: Three-hundred and fifty-five young men (1.77%) had COM. Other findings were retraction (n=66; 0.33%), adhesion (n=36; 0.18%), myringosclerosis (n=720; 3.6%) and cerumen (n=3200; 16%). We found out that five (0.025%) of the cases had radical mastoidectomy surgery and 16 (0.08%) of them had tympanoplasty. Conclusion: The prevalence of COM in young men is 1.77%. Although our study has a limitation because all of our samples are young men, the study is unique due to its large sample size. |
2. | Quality of life before and after surgery in patients with nasal polyposis Mehmet Özgür Pınarbaşlı, Hamdi Çaklı, Melek Kezban Gürbüz, Cemal Cingi, Erkan Özüdoğru Pages 277 - 284 FREE FULL TEXT Objectives: The postoperative symptoms, paranasal computed tomography (CT) findings and quality of life of the patients who had undergone surgical treatment for nasal polyposis were evaluated. Patients and Methods: This study included 32 patients (18 females, 14 males; mean age 43 years; range 14 to 64 years) who applied to our clinic between January 2008 and January 2009 and were operated on with diagnosis of pure nasal polyps. In addition, 36 healthy volunteers were randomized to the control group. The patients were evaluated before and after surgery, on the 3rd week and 3rd month with routine ear nose and throat physical examination and through the Short Form-36 (SF-36) questionnaire as the nasal symptom scores and quality of life. The SF-36 questionnaire was used in the control group as well. In this SF-36 questionnaire the patients were evaluated for eight domains. Control paranasal CT findings at 6th months after surgery were compared with the CT findings before surgery. Results: We determined improvement of nasal symptoms in patients (nasal obstruction, headache, loss of sense of smell, rhinorrhea and posterior rhinorrhea) at the 3rd week and 3rd month after surgery compared to before surgery (p<0.05). We also determined improvement in the domains of SF-36 questionnaire (general healthy, physical functioning, problems of emotional role, social functioning, pain, vitality and mental health) at the 3rd week and 3rd month after surgery compared to before surgery (p<0.05). Control paranasal CT findings of patients at 6th months after surgery was also improved significantly compared to before (p<0.001). Conclusion: We determined improvement in all symptoms and quality of life for a short period of time after the surgical treatment performed on patients with nasal polyposis. The paranasal CT has an important place for diagnosis and treatment. |
3. | Alterations of NIS expression in functioning thyroid nodules Hülya Ilıksu Gözü, Dilek Yavuzer, Handan Kaya, Selahattin Vural, Haluk Sargın, Cem Gezen, Mehmet Sargın, Sema Akalın Pages 285 - 292 FREE FULL TEXT Objectives: This study aimed to analyze both the level and the cell site of the sodium-iodide symporter (NIS) protein expression in autonomously functioning thyroid nodules (AFTNs) and extranodular thyroid tissues. In addition, this study sought to compare the clinical results of patients with the levels of human NIS (hNIS) protein expression. Patients and Methods: The histological slides consisted of 36 AFTNs and 31 extranodular thyroid tissues from 28 patients (5 males, 23 females; mean age 54.5±11.0 years; range 37 to 72 years) who underwent surgery for toxic multinodular goitre. The expression of NIS protein was investigated by immunohistochemistry in paraffinembedded tissue sections using anti-hNIS monoclonal antibody by the labeled streptavidin-biotin method. Results: The percentage of hNIS positive follicular cells was significantly higher in the AFTNs (13.33±12.09) than in the extranodular thyroid tissues (1.35±3.03). Staining for hNIS was mostly confined to the cell membrane in the AFTNs (88.9%) and in the extranodular thyroid tissues (54.5%). The clinical parameters and nodule volume did not establish any correlation with hNIS immunoreactivity. Conclusion: Our data indicate that functioning nodules express higher amounts of NIS protein than the extranodular thyroid tissue, but the level of hNIS immunoreactivity was lower than had been reported in the previous literature. This result may be due to interindividual variability between different populations, and iodine status. Furthermore, the localization of the NIS protein might not give an indication of its functional status. |
EXPERIMENTAL STUDY | |
4. | Reconstruction of large nasal septal perforations with a three layer galeal pericranial flap: an anatomical and technical study Bahar Keleş, Kayhan Öztürk, Aynur Emine Çiçekçibaşı, Mustafa Büyükmumcu Pages 293 - 298 FREE FULL TEXT Objectives: In this study, a modified surgical method was carried out to repair large nasal septal perforations with a galeal pericranial flap using endoscopic technique. Materials and Methods: Six adult human cadavers were dissected by applying the classic open rhinoplasty technique. Large perforations were created in the septal cartilages. To repair the perforations, we prepared galeal pericranial flaps with supraorbital neurovascular pedicles and calvarial bone grafts under endoscopic visualization. The flaps were inserted between the upper lateral cartilages and folded into three layers. The flaps were sutured to the nasal mucosa with absorbable sutures. The length, the width, the size of the flaps and the perforations were measured using an electronic caliper and a flexible ruler. Results: The mean length and width of the flap pedicles were measured as 26.8±5.1 mm (range 20 to 32 mm) and 19.3±2.6 mm (range 15 to 23 mm), respectively. In addition, the mean length and the width of the flaps were 54.1±4.9 mm (range 50 to 60 mm) and 51.6±7.8 mm (range 45 to 63 mm), respectively. All of the nasal septal perforations were repaired with a galeal pericranial flap. Conclusion: The galeal-pericranial flap is well-vascularized and similar to the nasal mucosa for tissue thickness. Therefore, reconstruction with galeal-pericranial flaps can be an alternative surgical technique for repair of large nasal septal perforations. |
5. | The effect of melatonin on experimentally-induced myringosclerosis in rats Kadir Çağdaş Kazıkdaş, Ensari Güneli, Kazım Tuğyan, Güven Erbil, Tuncay Küme, Nazan Uysal, Osman Yılmaz, Bülent Şerbetçioğlu Pages 299 - 304 FREE FULL TEXT Objectives: This study determined the preventive effect of melatonin on the occurrence of experimentally-induced myringosclerosis of the tympanic membrane (TM). Materials and Methods: Twenty Wistar albino-type rats weighing approximately 300 g each were randomly separated into two groups and myringotomized on the left TMs: group 1 rats (n=6) received intraperitoneal melatonin injections 10 mg/kg/day whereas group 2 rats (n=12) were treated with physiological serum only. The remaining two rats were served as the control group for histological comparison and standardization. After 15 days of treatment, myringotomized membranes were examined by otomicroscopy and harvested for histopathological evaluation. The functional effect of myringosclerotic plaques in the TMs of the two groups were compared with tympanometric measurements. Results: Tympanic membranes in group 2 revealed extensive myringosclerotic plaques, on the other hand, TMs in group 1 showed faint or no existence of myringosclerosis. The mean magnitude of the maximum admittance from group 2 measured by tympanometry reduced to about 40% of the values obtained from group 1 (Z=–2,067, p=0.041). The mean magnitude of the maximum admittance from melatonin group was very close to the mean tympanometric value of non-myringotomized Wistar albino rats, demonstrating a functional outcome. Conclusion: The occurrence of myringosclerosis following experimental myringotomy can be hindered by systemic melatonin treatment. |
CASE REPORTS | |
6. | Laser excision of a typical carcinoid tumor of the larynx: a case report Raşit Cevizci, Barış Karakullukçu, Michiel W.M. van den Brekel, Alfons J. Balm Pages 305 - 308 FREE FULL TEXT Neuroendocrine carcinomas of the larynx include a range of rare tumors which have variable biologic behavior, affecting treatment and prognosis. Among these, typical carcinoid tumors are the least common type. Prognosis of typical carcinoid tumor is better than atypical carcinoid tumor and small cell carcinoma of the larynx. Conservation surgery is the preferred treatment modality. Transoral CO2 laser surgery can be a good alternative for appropriate cases because of the functional results and less morbidity. In this article, a 71-year-old female presented with complaints of feeling a mass during swallowing. Fiberoptic examination of the larynx revealed a mass located on the right aryepiglottic fold and biopsy revealed the tumor as a typical carcinoid tumor. We describe CO2 laser excision of a typical carcinoid tumor of the larynx in this case report. |
7. | A rare cause of nasal obstruction: giant invasive nonfunctioning pituitary adenoma Güçlü Kaan Beriat, Cem Doğan, Şefik Halit Akmansu, Demet Karadağ, Handan Doğan Pages 309 - 313 FREE FULL TEXT Nasal obstruction is a very rare symptom caused by a pituitary adenoma. A 57-year-old man admitted to our clinic with bilateral nasal obstruction for the last six months. Endoscopic examination revealed soft pinkish pulsatile tissues in both nasal cavities. Radiologic investigation revealed a suprasellar mass extending to the frontal lobes, spheno-ethmoidal sinuses and nasal cavities. He had bitemporal superior quadrant hemianopsia. Pituitary hormone levels were normal. Biopsies were taken from the patient endonasally. Pathological evaluations and laboratory findings were compatible with nonfunctioning pituitary adenoma. |
8. | Management of laryngeal hemangioma in adults: a case report Murat Doğan, Ozan Bağış Özgürsoy, Sami Engin Muz, Muharrem Gerçeker, Gürsel Dursun Pages 314 - 317 FREE FULL TEXT Hemangiomas are the most common vascular tumors mostly (60%) seen in the head-neck region. Head-neck hemangiomas are seen frequently in the oral cavity, rarely in the larynx. Adult laryngeal hemangiomas are rare and often seen in the supraglottic region, therefore causing dysphagia/ dysphonia. We presented two-cases with laryngeal hemangioma, discussed the diagnosis, treatment and follow-up of adult cavernous hemangiomas. A forty-one-year-old female patient applied to hospital with hoarseness and breathing difficulty lasting for three years. A cavernous hemangioma located on laryngeal surface of the epiglottis was excised through a transoral endoscopic approach. The patient had no symptoms after the operation but on the postoperative 34th month follow-up she was admitted to our clinic again because of difficulty during swallowing. Relapsed hemangioma was diagnosed and reoperated by open surgery (laryngofissure). After reoperation the patient had symptomatic relief in three months and videolaryngoscopic examination showed granulation tissue. The patient’s regular follow-up was continued. A forty-year-old female other patient was applied to hospital with hoarseness and swallowing difficulty worsening in three months. Hemangioma located in the postcricoid area with extensive to hypopharynx-esophagus junction was diagnosed. The location of the lesion in imaging techniques was evaluated with the thoracic surgery and gastroenterology department and we decided not to do any operation and follow-up patient by considering the severity of symptoms, location of leison and complications of operation. |
9. | Nerve sheath myxoma of the upper lip: a case report Erkan Ekşi, İncila Öztop Pages 318 - 320 FREE FULL TEXT Nerve sheath myxoma is a benign tumor that rarely occurs in the lip area. In this article, a 28-year-old woman admitted with a complaint of painless swelling in the upper lip is presented. The lesion was excised, and histopathological and immunohistochemical examinations were performed. There are only five reported cases in the available literature. Although very rare, nerve sheath myxoma should be considered in the differential diagnosis of lip mass and widely excised to avoid local recurrence. The patient is under clinical control with no signs of recurrence after 16 months. |