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|2.||Frequency of frontal cells according to the International Frontal Sinus Anatomy Classification|
Engin Başer, Orkun Sarıoğlu, Cem Bulut, İlker Burak Arslan, İbrahim Çukurova
doi: 10.5606/Tr-ENT.2020.36349 Pages 33 - 40
INTRODUCTION: This study aims to determine the regional frequency of frontal cells classified by the International Frontal Sinus Anatomy Classification (IFAC) in local population radiologically
METHODS: Between February 2018 and May 2019, a total of 300 frontal recess regions of 150 adults (88 males, 62 females; mean age 33.5±9.4 years; range, 18 to 54 years) eligible for the inclusion criteria and undergoing paranasal sinus (PNS) computed tomography (CT) were included in the study. In CT analysis; agger nasi cells, supra agger cells, supra agger frontal cell, suprabullar cells, suprabullar frontal cells, supraorbital ethmoid cells and frontal septal cells were evaluated.
RESULTS: For anteriorly based cells, there were agger nasi cells, supra agger cells, and supra agger frontal cells with rates of 94.3% (n=283), 40.0% (n=120), and 14.7% (n=44), respectively. For posteriorly based cells, there were suprabullar cells, suprabullar frontal cells, and supraorbital ethmoid cells with rates of 59.7% (n=179), 7.3% (n=22) and 7.3% (n=22), respectively. For medially based cells, there were frontal septal cells with a rate of 29.3% (n=44).
DISCUSSION AND CONCLUSION: Our study results suggest that the regional prevalence of frontal cells classified by the IFAC in Turkish population can be determined radiologically, providing contribution to the generation of estimates of the global prevalence of frontal cells.
|3.||Is there any relationship between unilateral vestibular neuritis and internal acoustic canal measurements?|
Bayram Şahin, Selahattin Genç
doi: 10.5606/Tr-ENT.2020.54254 Pages 41 - 45
INTRODUCTION: In this study, we aimed to compare the internal acoustic canal (IAC) measurements of the affected and unaffected sides of patients with unilateral vestibular neuritis (VN) on magnetic resonance imaging (MRI).
METHODS: January 2017 and December 2019, a total of 120 patients (65 males, 55 females; mean age 58.3±12.5 years; range, 21 to 83 years) who were diagnosed with VN according to clinical findings, video head impulse test (vHIT), and MRI findings were enrolled in this study. All measurements were performed on the axial constructive interference in steady state (CISS) sequences. The IAC inlet, mid-canal, and outlet widths were measured at the most distinctive cross-section of the facial nerve and superior vestibular nerve bifurcation. While calculating the length of IAC, the points were taken on the basis of where the inlet and outlet widths of the canal were measured.
RESULTS: According to the vHIT results, a single semicircular canal (SCC) was affected in 102 (85%) patients, while more than one SCC was affected in 18 (15%) patients. The inlet, mid-canal and outlet values of the affected side were significantly lower than those of the unaffected side (p<0.05). Regarding the IAC length measurement, there was no significant differences between the affected and unaffected sides (p>0.05). All of these parameters were slightly higher in males; however, this difference was not statistically significant (p>0.05).
DISCUSSION AND CONCLUSION: Our study results showed that the widths of the IAC were lower in the affected side of patients with unilateral VN. These findings may help to explain why acute VN cases occur only unilaterally, suggesting that a small sectional diameter of the IAC is a potential risk factor for VN.
|4.||The effects of hyperbaric oxygen therapy on an experimental cisplatin-induced ototoxicity model|
Burak Dikmen, Hakan Avcı, Şaban Çelebi
doi: 10.5606/Tr-ENT.2020.62681 Pages 46 - 51
INTRODUCTION: This study aims to investigate the protective effect of hyperbaric oxygen therapy (HBOT) as an antioxidant agent on cisplatin ototoxicity.
METHODS: Between June 4th, 2014 and June 13th, 2014, a total of 15 adult female Wistar albino rats were used in this study. The rats were divided into the following groups: Group A comprised of five rats and had prophylactic one course of HBOT before intraperitoneal (IP) cisplatin injection, followed by two more courses of HBOT. Group B comprised of five rats receiving three cycles of HBOT after 10 mg/kg of IP cisplatin administration. Group C served as the control group, including five rats, and received 10 mg/kg IP cisplatin without any additional treatment. The distortion product otoacoustic emission amplitudes of the rats were obtained before and after the study.
RESULTS: Group A and Group C showed a significant decrease in all measurements (4,004 Hz, 4,761 Hz, 5,188 Hz, 5,652 Hz, 6,726 Hz, and 7,996 Hz) after cisplatin administration compared to that of baseline measurement. In Group B, a significant decrease was observed in the majority of the measurements, although no significant difference was found in 4,761 Hz.
DISCUSSION AND CONCLUSION: Our study results suggest that HBOT neither provides a protective nor therapeutic effect in a rat cisplatin-ototoxicity model.
|5.||Do serum copeptin levels change with positive airway pressure treatment in patients with severe obstructive sleep apnea?|
Üstün Osma, Ömer Tarık Selçuk, Mete Eyigör, Levent Renda, Nursel Türkoğlu Selçuk, Hülya Eyigör, Mustafa Deniz Yılmaz, Oguzhan İlden, Ünal Gökalp Işık, Hande Konsuk Unlu, Meral Gultekin
doi: 10.5606/Tr-ENT.2020.91885 Pages 52 - 57
INTRODUCTION: The aim of this study was to evaluate serum copeptin levels in patients with obstructive sleep apnea (OSA) before and after the positive airway pressure (PAP) treatment.
METHODS: A total of 16 patients (14 males, 2 females; median age 48 years; range, 38 to 60 years) with severe sleep apnea based on the Apnea Hypopnea Index (AHI) >30 and 20 healthy controls (10 males, 10 females; median age 35.5 years; range, 22 to 47 years) were included in this study between October 2014 and December 2015. Full-night polysomnography was applied to each patient. Serum copeptin levels were determined using the enzyme-linked immunosorbent assay in both groups. Serum copeptin level measurement was repeated in the patient group after one year of PAP treatment.
RESULTS: After one year of PAP treatment, serum copeptin levels of the patients with OSA decreased, although there was no statistically significant difference before and after treatment.
DISCUSSION AND CONCLUSION: Increased serum copeptin concentration may reflect a response to moderate stress in many diseases, particularly cardiovascular diseases. Based on our study results, there was no significant difference between the severe OSA group and healthy volunteers and before and after treatment among the patients with severe OSA.
|6.||Effect of sphenoid sinus volume and pneumatization type on isolated chronic sphenoid sinusitis (fungi and polyps)|
Engin Başer, Orkun Sarioglu, Mehmet İdil, İbrahim Çukurova, İlker Burak Arslan
doi: 10.5606/Tr-ENT.2020.51523 Pages 58 - 65
INTRODUCTION: In this study, we aimed to investigate the association of sphenoid volume and pneumatization type with pathologies, including unilateral isolated chronic sphenoid sinusitis with polyps (ICSSwP) and isolated fungal chronic sphenoid sinusitis (IFCSS).
METHODS: A total of 26 patients (15 males, 11 females; mean age 49.9±15.0 years; range, 18 to 80 years) with unilateral isolated sphenoid inflammation, pathologically diagnosed as IFCSS (n=14) or ICSSwP (n=12) between January 2010 and December 2018 were included in this study. The sphenoid sinus volumes of the pathological and normal sides of the patients were compared. The sphenoid pneumatization types were also evaluated.
RESULTS: In the IFCSS group, the pathological side volume was statistically significantly higher than the healthy side volume (p<0.05). In the ICSSwP group, the pathological side volume was statistically significantly lower than the healthy side volume (p<0.05).
DISCUSSION AND CONCLUSION: Large sphenoid sinus volume is prone to IFCSS, while smaller sphenoid sinus volume is prone to ICSSwP. Therefore, it should be considered that difference in the right and left sphenoid sinus volume may have different etiological or predisposing effects for different pathologies.
|7.||Laryngeal inflammatory myofibroblastic tumor mimicking advanced stage malignancy|
Ayşegül Gönen, Necati Enver, İrem Sahver İşgör, Leyla Cinel, Çağatay Oysu
doi: 10.5606/Tr-ENT.2020.51422 Pages 66 - 70
Inflammatory myofibroblastic tumors (IMTs), also known as inflammatory pseudotumors, plasma cell granulomas or inflammatory fibrosarcomas, are neoplastic lesions which primarily occur in children and are most frequently described in the lungs. They rarely affect the head and neck region. A 63-year-old female patient presented with an extremely large tumor which obstructed the airway. Total laryngectomy was performed. The diagnosis was atypical spindle cell proliferation and inflammatory cells without necrosis and an increased mitotic activity compatible with an IMT. The definitive diagnosis was achieved with positive cytoplasmic anaplastic lymphoma kinase-1 (ALK)-1 immunoreactivity. In conclusion, it is critical to evaluate patients carefully to distinguish IMT from mimicking diseases through endoscopic, radiological, histopathological, and immunohistochemical assessment to make tailor the treatment plan.
|8.||Recurrent malignant fibrous histiocytoma of vocal fold|
Suat Bilici, Muhammet Türe, Caner Aktaş, Özgür Yiğit, Erol Rüştü Bozkurt
doi: 10.5606/Tr-ENT.2020.29491 Pages 71 - 74
Malignant fibrous histiocytoma (MFH), which particularly involves the trunk and the upper and lower limbs, originates from the mesenchymal tissue. The larynx is one of the very rare locations. The disease has a poor prognosis due to local recurrence and metastasis. The first-line treatment is wide excision of the tumor. Herein, we report a case of MFH of the vocal fold in a 68-year-old man presenting with recurrence.
|9.||Primary acquired cholesteatoma causing facial paralysis in a three-year-old toddler: A rare case report|
Kerem Kökoğlu, Nezaket Tektaş, Mehmet İlhan Şahin
doi: 10.5606/Tr-ENT.2020.07752 Pages 75 - 79
Cholesteatoma is a disease characterized by the presence of squamous epithelium in the middle ear. It can be destructive and harm the temporal structures such as facial nerve, labyrinth, and ossicles, leading to possible complications. Facial nerve paralysis is one of these complications. Herein, we present a rare case of three-year-old toddler with a primary acquired cholesteatoma and facial nerve paralysis.