Objectives: We investigated the relationship between
positive skin test results and serum eosinophilic cationic
protein (ECP), nasal eosinophilia, and total IgE levels
in patients with allergic rhinitis.
Patients and Methods: The study included 36 patients
with allergic rhinitis (26 females, 10 males; mean age 32.8
years; range 17 to 60 years) and with a positive skin test
result. Serum ECP, nasal eosinophilia, and serum total
IgE levels were assessed and compared with a control
group of 18 healthy volunteers (15 females, 3 males;
mean age 30.3 years; range 20 to 49 years) and correlation
was sought with skin test results.
Results: Twenty-five patients were sensitive to only seasonal,
four patients to only perennial, and seven patients to
both seasonal and perennial allergens. Twelve patients
were sensitive to one allergen, seven patients to two, and
17 patients to three or more allergens. Compared to controls,
the mean serum ECP, nasal eosinophilia, and serum
total IgE values were significantly higher in the patient group
(p<0.05). These parameters did not show significant relationship
with the type and number of allergens (p>0.05).
Conclusion: Serum ECP, nasal eosinophilia, and
serum total IgE levels increase in patients with allergic
rhinitis. These parameters are not affected by sensitivity
to seasonal or perennial allergens.
FREE FULL TEXTAnahtar Kelimeler: Kan proteini/analiz; eosinofil; immünglobulinE/kan; burun mukozası; polen/yan etki; rinit, alerjik, perennial;deri testi.