E-ISSN 2602-4837
The Turkish Journal of Ear Nose and Throat Surgical treatment of hypopharyngeal cancer [Tr-ENT]
Tr-ENT. 2018; 28(3): 105-111 | DOI: 10.5606/Tr-ENT.2018.22931

Surgical treatment of hypopharyngeal cancer

Selçuk Güneş1, Bora Başaran2, İsmet Aslan2, Ökkeş Erkan Kıyak2
1Department of Otorhinolaryngology Head and Neck Surgery, Bakırköy Dr. Sadi Konuk Training and Research Hospital, İstanbul Turkey
2Department of Otorhinolaryngology Head and Neck Surgery, İstanbul University İstanbul Medical Faculty, İstanbul Turkey

INTRODUCTION: This study aims to evaluate our department’s approach to the treatment of hypopharyngeal tumors, the features of the tumors, the survival analyses and to present our results in the light of the literature.
METHODS: Eighty-one hypopharyngeal tumor patients and four patients with undefined primary origin, those patients with undefined origin have tumors that infiltrate both hypopharynx and cervical esophagus, totally 85 patients (56 males, 29 females; mean age 54.6±13.4 years; range, 23 to 81 years) who underwent surgical treatment, were included in this study. Demographic data, tumor characteristics, and treatment protocols were recorded retrospectively.
RESULTS: Patients were classified on the primary subsite of the hypopharynx: 51% originated from the sinus piriformis, 29% from the postcricoid area, 15% from the posterior wall of the pharynx and only 5% from the cervical esophagus. The relationship between sex and hypopharyngeal subsite was statistically significant (p<0.001); postcricoid tumors were more prominent in female patients. Also, patients with a history of tobacco use had a tendency for tumors originating from the piriform sinus (p<0.001). Additionally, highly significant differences were revealed between clinical and pathological T and N staging (p<0.001). Estimated 60-month survival rate was 45%.
DISCUSSION AND CONCLUSION: The majority of patients in the study group were not old-aged or alcohol consumers; particularly none of the female patients had any bad habit as a predisposing factor suggested in the etiology. The relationships between tumor site and smoking show that if the campaign against smoking is successful, the rate of sinus piriformis cancer will decrease. For a significant number of patients, primary surgical reconstruction was possible, which shortens postoperative recovery time and accelerates postoperative adjuvant therapy. Therefore, survival rates were found to be high.

Keywords: Esophageal reconstruction, hypopharynx cancer, organ preservation surgery; surgical treatment; survival

Selçuk Güneş, Bora Başaran, İsmet Aslan, Ökkeş Erkan Kıyak. Surgical treatment of hypopharyngeal cancer. Tr-ENT. 2018; 28(3): 105-111

Corresponding Author: Selçuk Güneş, Türkiye
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